【問題】How does poly(A) tail prevent degradation ?推薦回答

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Polyadenylation and Degradation of Human Mitochondrial RNA。

Here we asked whether human mitochondria retain truncated and transiently polyadenylated transcripts in addition to stable 3′-end poly(A) tails, which would be ...: tw | tw。

Translation of poly(A) tails leads to precise mRNA cleavage - NCBI。

2017年2月9日 · In general, poly(A) tails are not translated because most mRNAs encode a stop codon that terminates translation and prevents the ribosome from ...: tw | tw。

Phosphodiester modifications in mRNA poly(A) tail prevent ...。

2020年8月20日 · Chemical modifications enable preparation of mRNAs with augmented stability and translational activity. In this study, we explored how chemical ...。

tail length control to accentuate expression of the yeast transcriptome。

Control of poly(A) tail length can affect translation and stability of eukaryotic mRNAs. Although well established for individual cases, it was not known to ...。

Polyadenylation - Wikipedia。

mRNAs that are not exported are degraded by the exosome. Poly(A)-binding protein also can bind to, and thus recruit, several proteins that affect translation ...: 。

Poly(A) inclusive RNA isoform sequencing (PAIso−seq ... - Nature。

2019年11月22日 · Message RNA poly(A) tails are vital for their function and regulation. ... Therefore, it is better to avoid poly(A) enrichment to preserve ...。

TATA boxes in gene transcription and poly (A) tails in mRNA stability。

2015年12月16日 · Berberine (BBR) is a natural compound with variable pharmacological effects and a broad panel of target genes.。

Polyadenylation helps regulate functional tRNA levels in ...。

Furthermore, polyadenylation induces rapid degradation of 5S rRNA precursors but ... However, since dot blots do not detect poly(A) tails <15 nt in length, ...。

Enhanced stability and polyadenylation of select mRNAs support ...。

2015年1月27日 · To investigate how changes in rates of transcription and degradation could affect differential gene expression in torpor, we developed a ...。

The molecular basis of coupling between poly(A)-tail length and ...。

2021年1月19日 · Binding of PABPCs to mRNA poly(A) tails can enhance translation, ... necessary for PABPC1 to protect short-tailed mRNAs from degradation.


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